Introduction


The function of serum in cell cultures
  • Stimulates cell growth, proliferation and differentiation through hormonal factors
  • Adhesion factors facilitate and enhance cell attachment on culture dishes (bio-matrix)
  • Transport and binding proteins provide hormones, minerals and lipids
  • Inhibition of toxic substances by binding to serum proteins

Advantages of PAN-Seratech
  • Own raw material resources in different countries: Brazil, USA, Australia
  • Certificate of Suitability (COS) no. R1-CEP 2002-167-Rev 00
  • Licensed according to the EU-decree no. 1774/2002 with vet. no. DE 09 275 0001 14
  • Every single batch is fully documented – from the country of origin to the end product
  • We offer special types of serum: charcoal absorbed, delipidized, dialyzed, gamma irradiated, heat inactivated and gamma globulin reduced
  • Highest production and safety standards for serum manufacturing
  • Best references from industry and research
  • Extensive analyses and tests are presented in Certificate of Analysis (CoA)

Animal Sera
The dose of serum added to a cell culture as nutrient source depends on factors such as cell type, primary culture or cell line, adherent or suspension culture, and usually is in the range of 5 % to 15 % of the total liquid volume and most times used at 10 %. Serum is produced from animal blood and fetal bovine serum is the most widely used because it contains an especially high amount of growth factors due to its origin – the blood of fetuses is a by-product of slaughtered cattle. We exclusively use serum from guaranteed BSE-free collection areas. In addition, we can also confirm that South Africa, as a country of origin, is free from scrapie. No serum batches from Great Britain as the country of origin are processed by PAN-Seratech. We warrant the submission of a complete documentation, consisting of a certificate of origin and a veterinary certificate, shipping documents and a certificate of analysis. Furthermore, every single procedure during an individual production process is documented and then summarized in a production protocol.



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